Table 4. Lipid toxicity profile of AgNP-MSA-treated LACA albino mice. The results are expressed as the mean±standard error mean (P<0.01).
| Parameter | Control | 9 mg/kg b.w. | 10 mg/kg b.w. |
|---|---|---|---|
| AST (units/l) | 50.57±1.05 | 107.20±4.42 | 133.80±3.10 |
| ALT (units/l) | 23.52±0.66 | 56.20±2.06 | 63.60±1.08 |
| ALP (units/l) | 89.70±0.85 | 73.40±1.60 | 55.20±1.43 |
| Creatinine (mg/dl) | 0.68±0.04 | 0.63±0.02 | 0.43±0.03 |
| Proteins (g/dl) | 4.17±0.33 | 6.20±0.23 | 4.20±0.23 |
| TC (mg/dl) | 67.40±1.08 | 96.80±4.96 | 82.40±2.11 |
| TG (mg/dl) | 72.80±1.28 | 90.40±1.75 | 76.00±2.45 |
| HDL (mg/dl) | 23.20±0.86 | 55.00±3.08 | 33.40±1.60 |
| LDL (mg/dl) | 20.61±1.11 | 34.00±1.84 | 21.00±1.14 |
| VLDL (mg/dl) | 23.09±1.32 | 25.40±1.63 | 32.20±1.59 |
Abbreviations: AgNP, silver nanoparticle; ALP, alkaline phosphatase; ALT, alanine transferase; AST, aspartate transferase; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MSA, mouse serum albumin; TC, total cholesterol; TG, triglyceride; VLDL, very low-density lipoprotein.