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. 2015 Mar 16;13(2):217–228. doi: 10.1038/cmi.2015.07

Figure 4.

Figure 4

IL-4 increased the number and ratio of Vδ1 T cells in γδ T cells. (a) Both Vδ1 T cells and Vδ2 T cells were activated by immobilized anti-human TCR PAN γδ mAb and cultured with or without IL-4 for 12 days. The absolute number of Vδ1 T cells or Vδ2 T cells after 12 days culture was analyzed by flow cytometry. *P<0.05. (b) γδ T cells were activated by anti-human TCR PANγδ mAb with 0, 5 ng/ml, 10 ng/ml and 20 ng/ml IL-4 treatment (from left panel to right panel). The relative ratio of Vδ1 T cells to Vδ2 T cells was analyzed using a BD Accuri C6 flow cytometer. The data represent one of three independent experiments. TCR, T-cell receptor.