Table 1. lncRNAs in immune cell development.

lncRNA	Characteristics/functions	References
NRON	Acts as a scaffold lncRNA to block the transcriptional activity of NFAT in human T cells	20,21
LincR-Ccr2-5′AS	Controls the expression of immune genes in TH2 cells and regulates the migration of mouse TH2 cells into the lung	22
Tmevpg1 (NeST)	Influences TH1-lineage-specific expression of Ifng	23,24
linc-MAF-4	Acts as a scaffold to recruit and modulate the enzymatic activity of EZH2 on the MAF promoter, which regulates MAF transcription and promotes a CD4+ TH1 phenotype	25
lnc-DC	Controls human DC differentiation through interacting with STAT3 and promotes STAT3 phosphorylation by preventing STAT3 from binding to SHP1	26
NTT	Identified in human CD4+ T cells in 1997	19
GAS5	Is both necessary and sufficient for normal growth arrest in T-cell lines as well as human peripheral blood T cells	16
HOTAIRM1	Specifically expressed in myeloid cells	27
Multiple	Profiling of the lncRNA transcriptome by microarray was performed in 2009 and identified more than 1000 lncRNAs in human and mouse CD8+ T cells	28