TABLE 3.
Effects of individual shRNAs on perikaryal nascent protein synthesis
shRNA | Treatment |
|
---|---|---|
Vehicle | BDNF | |
Luc | 1 ± 0.04a,b | 1.098 ± 0.04a,b |
S6–1 | 0.567 ± 0.033c | 0.509 ± 0.029c |
S6–2 | 0.587 ± 0.027c | 0.58 ± 0.026c |
L4–1 | 0.883 ± 0.033a,b,d | 0.851 ± 0.039a,b,c |
L4–2 | 0.923 ± 0.046a,b | 0.846 ± 0.043a,b,c |
L11–1 | 0.949 ± 0.036a,b | 0.895 ± 0.035a,b,c |
L11–2 | 0.81 ± 0.038a,b,c | 0.703 ± 0.052a,b,c |
a p < 0.001 as compared with shS6-1.
b p < 0.001 as compared with shS6-2.
c p < 0.001 as compared with shLuc.
d p < 0.05 as compared with shLuc.