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. 2016 Jan 12;291(11):5721–5739. doi: 10.1074/jbc.M115.682161

TABLE 3.

Effects of individual shRNAs on perikaryal nascent protein synthesis

shRNA Treatment
Vehicle BDNF
Luc 1 ± 0.04a,b 1.098 ± 0.04a,b
S6–1 0.567 ± 0.033c 0.509 ± 0.029c
S6–2 0.587 ± 0.027c 0.58 ± 0.026c
L4–1 0.883 ± 0.033a,b,d 0.851 ± 0.039a,b,c
L4–2 0.923 ± 0.046a,b 0.846 ± 0.043a,b,c
L11–1 0.949 ± 0.036a,b 0.895 ± 0.035a,b,c
L11–2 0.81 ± 0.038a,b,c 0.703 ± 0.052a,b,c

a p < 0.001 as compared with shS6-1.

b p < 0.001 as compared with shS6-2.

c p < 0.001 as compared with shLuc.

d p < 0.05 as compared with shLuc.