FIGURE 3.
NEMOTS-KO mice kidney phenotype analysis. Shown are H&E staining (A) and immunohistochemical analysis (B) of the kidney markers NKCC2 and AQP2 in control and NEMOTS-KO kidney sections at 12 months of age (OM, outer medulla; IM, inner medulla). C, quantification of AQP2-positive cells in the collecting ducts of the inner medulla. The count was carried out on images acquired from five NEMOTS-KO and five control mice. Data shown are representative of at least three independent experiments. CTR, control. Error bars, S.E.