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. 2016 Jan 14;291(11):6011–6025. doi: 10.1074/jbc.M115.699215

FIGURE 2.

FIGURE 2.

Expression of PDK2 and PDK4 in neurons, infiltrated macrophages, and activated satellite glial cells in the diabetic DRG. Immunofluorescence analyses show the expression of PDK2 and PDK4 in neurons (A), infiltrated macrophages (B), and activated SGCs (C) in the DRG at 3 weeks post-STZ injection. PDK2 and PDK4 co-localized with MAP2 (a neuronal marker), Iba-1 (a macrophage marker), and GFAP (a SGC marker). Arrows indicate the representative double-labeled cells. Scale bars, 100 μm. The number of cells expressing PDK2 or PDK4 is presented in adjacent graphs. Images show the representative results of at least three independent experiments. *, p < 0.05 versus the vehicle-treated control animals, Student's t test, n = 3; mean ± S.E. (error bars). ND, not detected; MAP2, microtubule-associated protein 2.