Table 1. Outcomes of rodent studies providing information on effect of compulsory consumption of LES on BW.

	Change in BW relative to controls
	Decrease	No difference	Increase
At any dose (47)a	22	21	4
Lower LES doses (37)b	4	32	1
Higher LES doses (34)c	18	13	3

Abbreviations: BW, body weight; LES, low-energy sweetener.

Figures are numbers of studies reporting no difference or a significant change (increase or decrease) in BW relative to controls, with total numbers of relevant studies in brackets. Where a study used multiple LES doses (in some studies including doses both below and above 2% of vehicle), if the change in BW for any dose was significantly increased or decreased relative to placebo, that result was counted as the effect of the LES overall.

^aAll studies included in the count.

^bLower LES doses, ⩽2% of vehicle (diet or fluid source), only included in the count.

^cHigher LES doses, >2% of vehicle (diet or fluid source), only included in the count.