Table 2.

Effect of TMX-302 on cytokine/chemokine generation in the lung tissue of allergen-stimulated mice.

Cytokine (pg/lung tissue)	PBS	OVA	OVA + TMX-302	TMX-302
MIP-1-α	117.2 ± 76.4	937.5 ± 169+	1672.7 ± 295.1*	605.4 ± 84.9+
MIP-2	275.6 ± 70.6	665.6 ± 66.8+	243.9 ± 68.7*	934.9 ± 126.8+
TNF-α	88.7 ± 7.6	138.9 ± 11.0+	110.1 ± 8.7*	132.1 ± 11.2+

The analyses were performed 24 h after ovalbumin provocation, and values represent the mean ± SEM from at least six animals.

⁺p < 0.05 vs. PBS-challenge group.

*p < 0.05 vs. OVA-challenge group.