Table 5. Clinical course of the patients according to the OCTN2 haplotype.
| Parameter | Haplotype HChomozygosity (%) | Control (%) | OR (95% CI) | P valuea |
|---|---|---|---|---|
| Total number | 11 | 182 | ||
| Behavior | ||||
| Inflammatory | 4 (36.4) | 105 (57.7) | ||
| Stricturing | 2 (18.2) | 42 (23.1) | 1.294b (0.226–7.423) | 0.772 |
| Penetrating | 5 (45.5) | 35 (19.2) | 4.239b (1.052–17.076) | 0.042c |
| Azathioprine or anti-TNF use | 9 (81.8) | 135 (74.2) | 1.608 (0.324–7.968) | 0.561 |
| Surgery | 8 (72.7) | 56 (30.8) | 7.542 (1.885–30.172) | 0.004d |
aAfter adjustment for other covariates (i.e. sex, age of onset, and BMI).
bOR of multinomial logistic regression model with the inflammatory type as a reference category of outcome variable.
cAdjusted P = 0.084 after Benjamini-Hochberg correction.
dSignificant after Benjamini-Hochberg correction (adjusted P = 0.016).