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. 2016 Mar 11;6:22887. doi: 10.1038/srep22887

Table 5. Clinical course of the patients according to the OCTN2 haplotype.

Parameter Haplotype HChomozygosity (%) Control (%) OR (95% CI) P valuea
Total number 11 182    
Behavior        
 Inflammatory 4 (36.4) 105 (57.7)    
 Stricturing 2 (18.2) 42 (23.1) 1.294b (0.226–7.423) 0.772
 Penetrating 5 (45.5) 35 (19.2) 4.239b (1.052–17.076) 0.042c
Azathioprine or anti-TNF use 9 (81.8) 135 (74.2) 1.608 (0.324–7.968) 0.561
Surgery 8 (72.7) 56 (30.8) 7.542 (1.885–30.172) 0.004d

aAfter adjustment for other covariates (i.e. sex, age of onset, and BMI).

bOR of multinomial logistic regression model with the inflammatory type as a reference category of outcome variable.

cAdjusted P = 0.084 after Benjamini-Hochberg correction.

dSignificant after Benjamini-Hochberg correction (adjusted P = 0.016).