TABLE 2.

Diagnostic and laboratory findings for 25 reported cases of Baylisascaris procyonis neural and visceral larva migrans^a

Patient no./yrb/sex/age/location	Funduscopic exam result	Blood eosinophilia (%)	CSF eosinophilia (%)	Serology for B. procyonisc	Chest radiography result	Reference(s)
1/1973/F/18 mos/Missouri	NR	30	49, 80, 34, 100	Positive for Ascaris by bentonite flocculation, S = 1:160, C = 1:10	Mild right perihilar infiltrate	5, 7, 8, 13
2/1980/M/10 mos/Pennsylvania	Optic atrophy later	27	68	S = strong positive by IFA	NR	5–8, 34
3/1984/M/18 mos/Illinois	Normal	37, 34	NR, 50, 80	S = positive by IFA and later by ELISA, S = 1.635d	Normal	5–8, 35
4/∼1985/M/21 yrs/Oregon	NR	NR	NR	S = positive by ELISA, 1.800	NR	5, 6, 7, 33; K. D. Thomson, unpublished data and written communication to K. R. Kazacos (2005, 2010)
5/1990/M/13 mos/New York	Normal	39	60, 52	Positive by EIA (Western blotting; S = >1:10, 240, C = 1:40–80) and later by ELISA (S = 2.600–2.961, C = 1.655–1.689)	Normal	5–8, 33
6/1993/M/13 mos/California	R, diffusely mottled retina, reddish macular lesion, optic pallor	45	Prominent eosinophilia	S = positive by IFA (1:1,024) and ELISA (0.809, 1:102, 400)	Mild bihilar and right middle lobe infiltrates	5–8, 36
7/1993/M/9 mos/Michigan	Normal	29, 33, 43, 40	many eosinophils, 85, 89, 62, 71	S = positive by ELISA, 3.113	Normal	5, 6, 8; J. M. Proos and C. Gushurst, unpublished data (1993) and written communication to K. R. Kazacos (1993–1994)
8/∼1994/M/10 yrs/Massachusetts	ND	15	ND	ND	NR	5, 7, 8, 37
9/1996/M/6 yrs/Illinois	L, DUSN	5 (post-3.5 yrs)	6 (post-3.5 yrs)	Positive later by IFA (S = 1:4,096, C = 1:64) and by ELISA (S = 2.230, C = 1.114)	NR	5–8, 38
10/1996/M/13 mos/Minnesota	Normal	35, 14, 12	54, 73, 4, 6	Positive by IFA (S = 1:1,024–4,096; C = 1:64) and by ELISA (S = 1.361, C = 0.438, 1.333)	NR	5–8, 39
11/1997/M/19 mos/Minnesota	Normal	18, 22, 22, 26	4, 19, 13, 5, 67	Positive by IFA (S = 1:4,096, C = 1:64–256) and by ELISA (S = 2.316, C = 0.289–0.795)	NR; CT normal	5–8, 39
12/1998/M/11 mos/California	R, DUSN, with chorioretinal scarring, linear track lesions, optic atrophy	17, 17	6, 7	Positive by IFA (S = 1:64–1,024, C = 1:64) and by ELISA (S = 1.334, 2.574, C = 0.128)	NR	5–8, 40
13/2000/M/2.5 yrs/Illinois	R, Multifocal choroiditis with infiltrates	28, 6	32, 26	Positive by IFA (S = 1:1,024–4,096, C = 1:1,024) and by ELISA (S = 3.132–3.218, C = 1.888, 2.021)	Normal	5–8, 38, 41
14/2000/M/17 yrs/California	ND	15	37, 42	Positive by IFA (S = 1:4,096, C = 1:256) and by ELISA (S = 3.025, 3.035, C = 1.746, 1.765)	ND	5–8, 41; W. A. Kennedy, unpublished data (2001) and written communication to K. R. Kazacos (2001)
15/2002/M/11 mos/California	Normal	30, 30	23, 54, 33	Positive by ELISA, S = 1.869, 2.451, C = 0.624–1.017	ND	5–8; K. R. Kazacos, unpublished data (2002–2004); D. Paul, unpublished data (2003) and written communication to K. R. Kazacos (2003)
16/2004/M/4 yrs/Louisiana	NR	12	55	Positive by ELISA, S = 0.547, 0.976	NR	42
17/2004/F/15 mos/New York	NR	Marked eosinophilia	Eosinophilia	Positive by ELISA, S = 1.921–2.556, C = 0.175, 0.347	NR	43; C. J. Crosley, unpublished data (2004) and written communication to K. R. Kazacos (2004)
18/2005/M/7 yrs/Ontario	Bilateral patchy subretinal infiltrates	24, 21, 8	30, 7	Positive by ELISA (S = 1.813, C = 0.186, 0.723) and by Western blotting	NR	8, 44
19/2007/M/17 yrs/Oregon	Bilateral subtle edema of optic discs	8, 21	49, 39	Positive by ELISA (S = 2.376, C = 0.600) and by Western blotting	Normal	45
20/2007/F/18 mos/Missouri	NR	Profound eosinophilia	40	Positive by ELISA (S = 2.130, 2.164, C = 1.919) and by Western blotting	NR	46; M. A. Jackson, unpublished data (2007) and written communication to K. R. Kazacos (2007)
21/2008/M/12 mos/New York	Normal	30, 24	29, 46, 19	Positive by ELISA, S = 1.385, C = 1.453	Normal	47
22/2008/M/14 mos/Massachusetts	Normal	24, 10, 4	24	S = Positive by ELISA with rising titer (0.243–0.500) and by Western blotting	NR	48, 49
23/2008/M/14 mos/Ontario	Normal	32	NR	Positive by ELISA (S = 0.744, C = neg) and by Western blotting	NR	50
24/2009/M/54 yrs/Missouri	NR	NR	Normal	ND	NR	51; M. Cohen, unpublished data (2009) and written communication to K. R. Kazacos (2011)
25/NR/F/73 yrs/British Columbia	NR	NR	NR	ND	NR	52

^aCSF; cerebrospinal fluid; R, right eye; L, left eye; NR, not reported; ND, not done; IFA, indirect immunofluorescence assay; ELISA, enzyme-linked immunosorbent assay; DUSN, diffuse unilateral subacute neuroretinitis; EIA, enzyme immunoassay; CT, computed tomography; neg, negative.

^byr, year of onset or presentation.

^cData include unpublished ELISA results from K. R. Kazacos. S, serum; C, CSF.

^dFor ELISA, the value is the optical density (OD) reading, where an OD of >0.250 is considered positive for serum.