Figure 2 |
Vaginal opening from 18 to 29 days of age. Body weight to 8 weeks of age |
Control: 29 10 ppb: 37 42.5 ppm: 35 |
Figure 3 |
LH, FSH, and estradiol |
Control: 5–6 10 ppb: 5–6 42.5 ppm: 4–8 |
Figure 4A |
Body weight from 9 to 15 weeks of age |
Control: 17 10 ppb: 25 42.5 ppm: 21 |
Figure 4B |
Body fat composition at 4.5 months of age |
Control: 9 10 ppb: 10 42.5 ppm: 14 |
Figure 4C |
Glucose tolerance at 5 months of age |
Control: 7 10 ppb: 10 42.5 ppm: 11 |
Figure 5 |
Body weight and levels of leptin and insulin at 6 months of age |
Control: 5 10 ppb: 7 42.5 ppm: 6 |
Table 2 |
Estrous cyclicity for 18 days starting at 10 weeks of age |
Control: 17 10 ppb: 22 42.5 ppm: 21 |
Table 3 |
Fertility: number of litters, total number of pups per litter, total number of pups per female, days between litters, and fertile period |
Control: 5 10 ppb: 8 42.5 ppm: 13 |
Sup Figure S1A,B |
Maternal weight gain and litter size |
Control: 7 10 ppb: 7 42.5 ppm: 7 |
Sup Figure S1C |
Fetal body weight at E18 |
Control: 46 10 ppb: 30 42.5 ppm: 38 |
Sup Figure S2 |
Ovarian histology at 21 days, 28 days, and 6 months of age |
Control: 5 10 ppb: 7 42.5 ppm: 6 |
Sup Figure S3 |
Serum levels of estradiol, testosterone, progesterone, and DHEA at 6 months and 1 year of age |
Control: 5 10 ppb: 7 42.5 ppm: 6 |
DHEA, dehydroepiandrosterone; E18, embryonic day 18; FSH, follicle-stimulating hormone; LH, luteinizing hormone; Sup, Supplemental Material. |