Table 3.
Estimates from GEEb modles of indicators of pain, constipation, vomiting, dyspnea, and anorexia
| Pain | Constipation | Vomiting | Dyspnea | Anorexia | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| N | β(SE)a | P-value | β(SE)a | P-value | β(SE)a | P-value | β(SE)a | P-value | β(SE)a | P-value | |
| Age, year | |||||||||||
| < 65 | Reference | - | Reference | - | Reference | - | Reference | - | Reference | - | |
| ≥ 65 | −0.23 (0.06) | < 0.001 | −0.19 (0.08) | 0.087 | −0.06 (0.12) | 0.614 | 0.07 (0.09) | 0.428 | 0.04 (0.06) | 0.475 | |
| Gender | |||||||||||
| Male | 480 | Reference | - | Reference | - | Reference | - | Reference | - | Reference | - |
| Female | 344 | 0.01 (0.06) | 0.828 | 0.18 (0.12) | 0.129 | 0.32 (0.16) | 0.046 | −0.06 (0.09) | 0.548 | 0.23 (0.06) | < 0.001 |
| Cancer | |||||||||||
| Lung cancer | 150 | Reference | - | Reference | - | Reference | - | Reference | - | Reference | - |
| Gastrointestinal cancer | 267 | 0.12 (0.08) | 0.146 | 0.21(0.11) | 0.044 | 0.90 (0.16) | < 0.001 | −0.36 (0.12) | 0.002 | 0.59 (0.09) | < 0.001 |
| Breast cancer | 55 | 0.02 (0.13) | 0.875 | −0.20 (0.19) | 0.287 | 0.41 (0.23) | 0.075 | 0.12 (0.18) | 0.507 | −0.07 (0.15) | 0.638 |
| Genitourinary cancer | 108 | 0.03 (0.10) | 0.777 | 0.10 (0.14) | 0.469 | 0.79 (0.19) | < 0.001 | −0.45 (0.15) | 0.002 | 0.19 (0.12) | 0.102 |
| Head, neck, and oral cancer | 185 | 0.15 (0.09) | 0.108 | 0.10(0.13) | 0.452 | −0.25 (0.22) | 0.245 | −0.22 (0.13) | 0.089 | −0.15 (0.13) | 0.242 |
| Other cancers | 59 | −0.02 (0.12) | 0.836 | 0.09 (0.21) | 0.684 | −0.10 (0.34) | 0.773 | −0.22(0.15) | 0.140 | 0.48 (0.13) | < 0.001 |
| Day of palliative care | |||||||||||
| 1st day | 822 | Reference | - | Reference | - | Reference | - | Reference | - | Reference | - |
| 3rd day | 824 | −0.45 (0.02) | < 0.001 | −0.20 (0.08) | 0.013 | −0.35 (0.05) | < 0.001 | −0.22 (0.03) | < 0.001 | −0.18 (0.02) | < 0.001 |
| 5th day | 823 | −0.67 (0.03) | < 0.001 | −0.22 (0.04) | < 0.001 | −0.47 (0.08) | < 0.001 | −0.25 (0.04) | < 0.001 | −0.23 (0.03) | < 0.001 |
| 7th day | 822 | −0.98 (0.04) | < 0.001 | −0.21 (0.06) | < 0.001 | −1.04 (0.09) | < 0.001 | −0.02 (0.05) | 0.658 | −0.18 (0.04) | < 0.001 |
a Adjusted mean difference compared to referent group. bGEE:generalized estimating equation