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. Author manuscript; available in PMC: 2016 Mar 11.
Published in final edited form as: Nat Med. 2015 Dec 21;22(1):46–53. doi: 10.1038/nm.4011

Figure 6.

Figure 6

Rolipram treatment improves cognition in rTg4510 mice with early-stage disease. Cognitive performance, assessed by Morris water maze escape latency, of rTg4510 and WT mice treated with vehicle or rolipram. n = 16 (vehicle) or 15 (rolipram) in rTg4510 mice group; and n = 7 (vehicle) or n =7 (rolipram) in WT mice group. Error bars, mean ± s.d. **P < 0.01 (repeated-measures ANOVA test (days 1–3) plus one-way ANOVA with Bonferroni correction (day 4)).