TABLE 1.
Effects of LPS on the release of VEGF-A, VEGF-C, Ang1, Ang2, TNF-α, IL-6, and IL-8/CXCL8 from HLM
| Variable | Untreated | LPS |
|---|---|---|
| VEGF-A (pg/mg of protein) | 37.2 ± 12.2 | 105.1 ± 22.5a |
| VEGF-C (pg/mg of protein) | 165.8 ± 9.7 | 279.5 ± 26.1a |
| Ang1 (pg/mg of protein) | 165.3 ± 28.6 | 390.3 ± 56.3a |
| Ang2 (pg/mg of protein) | 170.7 ± 47.1 | 455.6 ± 99.7a |
| TNF-α (ng/mg of protein) | 1.7 ± 0.6 | 35.0 ± 5.7a |
| IL-6 (ng/mg of protein) | 5.9 ± 2.3 | 63.4 ± 29.1a |
| IL-8/CXCL8 (ng/mg of protein) | 165.3 ± 59.9 | 431.0 ± 72.8a |
Data represent the mean ± sd of 6 independent experiments.
a
P < 0.01 vs. corresponding value of untreated HLM.