Figure 1.

Algorithm for Treatment of Hyponatremia Guided by Clinical Severity 1. Treatment of dilutional hyponatremia in psychiatric patients. * The severity of symptoms is related to the rate of development of the hypo-osmolality; the serum [Na⁺] at which symptoms appear varies markedly among individuals, although most patients demonstrate symptoms when the serum [Na⁺] falls below 125 mEq/L. ** The rate of correction of hyponatremia should not exceed a maximum of 10 to 12 mEq/L in 24 hours. Adapted from: Siegel AJ: Hyponatremia in psychiatric patients: update on evaluation and management. Harv Rev Psychiatry, 2008; 16: 13–24.