Table 3.
Hemodynamic Characteristics of Patients Experiencing and Not Experiencing an Adverse Event.
| Major Adverse Event |
||||
|---|---|---|---|---|
| No. (%) (N =19,608; SV=3,775) | Yes (n=378; SV=102) | No (n= 19,230; SV=3,673) | P value | |
| Systemic Ventricular EDP-- mean± s.d.* | 10.8 ± 4.9 | 11.5 ± 6.1 | 10.8 ± 4.9 | 0.04 |
| Cardiac Index-- mean± s.d.† | 3.8 ± 1.3 | 3.7 ± 1.4 | 3.8 ± 1.3 | 0.11 |
| Single Ventricle Hemodynamic Data | ||||
| Systemic Saturation-- mean± s.d.‡ | 83.3 ± 10.3 | 76.5 ± 16.1 | 83.5 ± 10.0 | <0.001 |
| Mixed Venous Saturation-- mean± s.d.§ | 61.3 ± 11.2 | 54.1 ± 13.9 | 61.5 ± 11.0 | < 0.001 |
| MPA Mean Pressure -- mean± s.d.∥ | 16.0 ± 7.4 | 19.0 ± 8.7 | 15.9 ± 7.3 | < 0.001 |
| Non-Single Ventricle Hemodynamic Data | ||||
| Systemic Saturation-- mean± s.d.# | 94.7 ± 7.1 | 92.4 ± 10.5 | 94.7 ± 7.0 | < 0.001 |
| Mixed Venous Saturation-- mean± s.d.** | 70.3 ± 9.4 | 65.3 ± 13.6 | 70.3 ± 9.3 | < 0.001 |
| MPA Systolic Pressure -- mean± s.d.*** | 31.5 ± 16.7 | 38.1 ± 22.6 | 31.4 ± 16.6 | < 0.001 |
| Systemic Ventricular EDP ≥ 18mmHg | 0.005 | |||
| Yes-- no. (%) | 988 ( 5.0) | 27 (7.1) | 961 (5.0) | |
| No-- no. (%) | 11,332 (57.8) | 189 (50.0) | 11,143 (57.9) | |
| Missing-- no. (%) | 7,288 (37.2) | 162 (42.9) | 7,126 (37.1) | |
| Saturation <95% (non-SV) or <78% (SV) | <0.001 | |||
| Yes-- no. (%) | 4,894 (25.0) | 128 (33.9) | 4,766 (24.8) | |
| No-- no. (%) | 12,765 (65.1) | 191 (50.5) | 12,574 (65.4) | |
| Missing-- no. (%) | 1,949 (9.9) | 59 (15.6) | 1,890 (9.8) | |
| MV Saturation <60% (non-SV) or <50% (SV) | ||||
| Yes-- no. (%) | 2,131 (10.9) | 90 (23.8) | 2,041 (10.6) | <0.001 |
| No-- no. (%) | 14,856 (75.8) | 210 (55.6) | 14,646 (76.2) | |
| Missing-- no. (%) | 2,621 (13.4) | 78 (20.6) | 2,543 (13.2) | |
| PA Systolic Pressure ≥45 (non-SV) or Mean Pressure ≥17mmHg (SV) | <0.001 | |||
| Yes-- no. (%) | 2.933 (15.0) | 85 (22.5) | 2.848 (14.8) | |
| No-- no. (%) | 13.046 (66.5) | 171 (45.2) | 12.875 (67.0) | |
| Missing-- no. (%) | 3.629 (18.5) | 122 (32.3) | 3.507 (18.2) | |
Abbreviations: no., number; s.d, standard deviation; SV, single ventricle; EDP, end diastolic pressure; MPA, main pulmonary artery; PA, pulmonary artery
7, 288 patients (162 with and 7,126 without adverse events) with missing information for systemic ventricular EDP
4,179 patients (134 with and 4,045 without adverse events) with missing information for cardiac index
301 patients (15 with and 286 without adverse events) with missing information for SV systemic saturation
476 patients (23 with and 453 without adverse events) with missing information for SV mixed venous saturation
811 patients (31 with and 780 without adverse events) with missing information for SV MPA mean pressure
1.648patients (44 with and 1604 without adverse events) with missing information for non-SV systemic saturation
2.145 patients (55 with and 2.090 without adverse events) with missing information for non-SV mixed venous saturation
2.818 patients (91 with and 2.727 without adverse events) with missing information for non-SV MPA systolic pressure