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Synthesis of protein array using an anti-Her2 Fab with site-specific incorporation of pAcF. An excess of synthesized aminooxy-DNA compound (Scheme S1) is added to anti-Her2 pAcF Fab and incubated at 37 °C for 16 h. After purification, the anti-Her2-oligonucleotide conjugate is added to the array and annealed to its complementary strand. Her2 positive tumor cells can then be captured and analyzed.
