Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Quantification of conformational changes in human and worm Ago structures associated with target recognition. Ago–Ago RMSD values for: (A) Agos at all targets superimposed with a reference structure (AGO1 (4KRF) for human and modeled ALG-2 for worm). (B) Agos binding the same targets. (C) Agos binding different targets. (D) Agos associated with a let-7 guide miRNA binding to different targets. In all cases, 5 model miRISC structures were assessed for each target.
