Table 1. Summary of efn-4 alleles used in this study.
| efn-4 allele | Nature of mutation | Phenotypea |
|---|---|---|
| e1746 | A75V | Weak (temperature sensitive) |
| e660 | P54L | Intermediate |
| bx80 | 1839-bp deletion | Strong (predicted null) |
| e36 | Y69ochre | Strong |
| ju134 | T72I | Strong |
The bx80 deletion removes all of exon 2 from the efn-4 locus and is predicted to create a frameshift at the exon 1-to-exon 3 splice junction, generating a premature stop codon.
a
Phenotypic penetrance based on embryonic lethality data summarized in Chin-Sang et al. (2002).