Figure 8.

Graphical model of BIR1 and BAK1 function . (A) BIR1 acts as a negative regulator of BAK1 function as a coreceptor for ligand-binding RLKs, such as FLS2, that control pathogen-triggered immune response pathways that include EDS1 and PAD4. High temperature also negatively regulates this response, and LR development is negatively affected by PTI response. (B) BIR1 positively regulates BAK1 function as a coreceptor for BRI1, positively regulating primary root growth, and BIR1 also may positively affect BR-independent root growth via BAK1/SERK interaction with an unknown RLK.