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. 2016 Mar 11;10(3):e0004535. doi: 10.1371/journal.pntd.0004535

Fig 4. TEM of E. multilocularis metacestodes: Non-treated or treated with 0.4 μM MMV665807.

Fig 4

Non-treated metacestodes (A-C) or metacestodes treated with 0.4 μM MMV665807 for 5 days (D) are shown. (A) is a low magnification view of a section through a non-treated metacestode wall, showing the laminated layer (LL), tegument (Te) and the germinal layer (GL). Clearly visible are undifferentiated stem cells (uc) and the microtriches protruding from the tegument well into the LL (arrows). Bar = 4 μm. Undifferentiated stem cells are shown at higher magnification in (B). mi = mitochondria; nu = nucleus with nucleolus. Bar = 1.5 μm. Higher magnification view of mitochondria are shown in (C). mi = mitochondria, yellow arrows point towards the cristae embedded in an electron matrix. Bar = 0.3 μm. (D) shows a representative micrograph of a metacestode exposed to 0.4 μM MMV665807 for 5 days. Arrows point towards microtriches, mi = mitochondria, mu = muscle cell. Bar = 2.2 μm.