Table 2. Histopathological results of H. felis re-infected BALB/c Plcg2Ali5/+ and WT mice.
Group | Re-infection | Genotype | Number of mice | Normal findings | Lymphoid aggregates | MALT lymphoma | |
---|---|---|---|---|---|---|---|
Enrolleda | Diedb | ||||||
4 | 4 times within 12 months | Plcg2 Ali5/+ | 11 | 1 | 40% (4/10) | 60% (6/10) | 0% |
WT | 11 | 0 | 46% (5/11) | 54% (6/11) | 0% |
BALB/c Plcg2Ali5/+ and WT mice were orally infected with H. felis. Mice were re-infected with H. felis in a 3 months interval for totally 12 months. Normal finding indicates healthy gastric mucosa.
Statistical analysis was done with Fisher´s exact test (comparison of genotypes for MALT lymphoma development with lymphoid aggregates) Plcg2Ali5/+ versus WT mice p = 1.
a Number of mice enrolled at the beginning of the study.
b Number of mice that died during infection time. A histological investigation of these mice was not possible.