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. 2016 Mar 7;11:905–918. doi: 10.2147/IJN.S100350

Figure 5.

Figure 5

Neuronal differentiation in retinas following exposure to copper oxide nanoparticles.

Notes: (A–I) Sections taken through the retinas at 72 hours postfertilization. (A, D, and G) Zn12 staining; (B, E, and H) Zpr1 staining; and (C, F, and I) Zpr3 staining. (J–L) Note that there were fewer Zn12-positive, Zpr1-positive, and Zpr3-positive cells in treated compared to unexposed retinas. Scale bar: (A–I): 50 µm. *P<0.05.

Abbreviations: DAPI, 4′,6-diamidino-2-phenylindole; GCL, ganglion cell layer; INL, inner nuclear layer; L, lens; ON, optic nerve; ONL, outer nuclear layer.