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. Author manuscript; available in PMC: 2016 Mar 11.
Published in final edited form as: Psychiatr Serv. 2014 Nov 17;65(12):1433–1438. doi: 10.1176/appi.ps.201400044

Table 1.

Status of Drugs in Phase III Development for Selected Psychiatric Disorders

Disorder a Total number of
open or active
Phase III drug trials
Classification of those drugs in open or active Phase III drug
trials

Number of
drugs under
study b
Number of drugs
not yet approved
by the FDA for
any purpose c
Number of new drugs
representing
substantial departure
from existing
treatment
Alcohol use disorders 11 9 0 0
Anxiety 8 7 0 0
ADHD 3 2 0 0
Bipolar Disorder 17 13 0 0
Depression 23 18 4 1
Insomnia 5 9 1 0
Schizophrenia 32 10 5 2
a

Some trials are found under multiple disorders (e.g., treatment for comorbid alcohol and PTSD).)

b

Some drugs are studied in combination with other drugs that are also counted.

c

Also excluded from this count are any drugs currently marketed as supplements.