Abstract
National potato tuber blight scores in the Republic of Ireland for the years 1961-70 were ascertained and evaluated in relation to incidence of anencephalic births in the following years. No significant relationship between annual tuber blight scores and incidence of anencephaly one year later could be demonstrated. Examination of the records of a maternity hospital for the years before, during, and after the great midnineteenth century potato famine in Ireland failed to show any appreciable fluctuation in anencephaly/spina bifida incidence during this period.
Full text
PDF



Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- COFFEY V. P., JESSOP W. J. A study of 137 cases of anencephaly. Br J Prev Soc Med. 1957 Oct;11(4):174–180. doi: 10.1136/jech.11.4.174. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Carter C. O., David P. A., Laurence K. M. A family study of major central nervous system malformations in South Wales. J Med Genet. 1968 Jun;5(2):81–106. doi: 10.1136/jmg.5.2.81. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Elwood J. H., MacKenzie G. Letter: Associations between the incidence of neurological malformations and potato blight outbreaks over 50 years in Ireland. Nature. 1973 Jun 22;243(5408):476–477. doi: 10.1038/243476a0. [DOI] [PubMed] [Google Scholar]
- GUTHKELCH A. N. Studies in spina bifida cystica. III. Seasonal variation in the frequency of spina bifida births. Br J Prev Soc Med. 1962 Jul;16:159–162. doi: 10.1136/jech.16.3.159. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Poswillo D. E., Sopher D., Mitchell S. J., Coxon D. T., Curtis R. F., Price K. R. Further investigations into the teratogenic potential of imperfect potatoes. Nature. 1973 Aug 10;244(5415):367–368. doi: 10.1038/244367a0. [DOI] [PubMed] [Google Scholar]
- Poswillo D. E., Sopher D., Mitchell S. Experimental induction of foetal malformation with "blighted" potato: a preliminary report. Nature. 1972 Oct 20;239(5373):462–464. doi: 10.1038/239462a0. [DOI] [PubMed] [Google Scholar]
- Renwick J. H. Hypothesis: anencephaly and spina bifida are usually preventable by avoidance of a specific but unidentified substance present in certain potato tubers. Br J Prev Soc Med. 1972 May;26(2):67–88. doi: 10.1136/jech.26.2.67. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rogers S. C., Morris M. Infant mortality from spina bifida, congenitalhydrocephalus, monstrosity, and congenital dseases of the cardiovascular system in England and Wales. Ann Hum Genet. 1971 Feb;34(3):295–305. doi: 10.1111/j.1469-1809.1971.tb00242.x. [DOI] [PubMed] [Google Scholar]
