Table 4. Median and coefficient of variation (CV) of parameter estimates (n = 1200; i.e. 100 replicates for each setting and each model) under static or dynamic condition.

			Model 1		Model 2		Model 3		Model 4		Model 5		Model 6
Parameter	True value	Unit	Static	Dynamic	Static	Dynamic	Static	Dynamic	Static	Dynamic	Static	Dynamic	Static	Dynamic
MGT	60	min	60.57 (8)	60.97 (10.7)	60.49 (8.9)	68.46 (20)	69.41 (13)	61.23 (9.0)	73.03 (11.8)	60.86 (9.7)	60.97 (12.0)	60.66 (9.9)	61.52 (6.0)	62.22 (11.8)
Inoc	6	Log10 CFU/mL	6.00 (0.48)	6.00 (1.8)	6.00 (0.4)	6.01 (1.6)	6.00 (0.4)	5.99 (2.3)	6.01 (0.5)	6.02 (2.0)	6.01 (0.6)	5.99 (2.0)	6.00 (0.6)	5.99 (2.3)
Popmax	9.5	Log10 CFU/mL	9.53 (1)	8.96 (19.8)	9.52 (1.09)	10.9 (15.9)	9.50 (0.87)	9.49 (4.4)	9.49 (0.9)	9.54 (10)	9.51 (0.7)	9.51 (8.8)	9.51 (0.76)	9.51 (1.3)
kmax	4	h-1	3.94 (4.2)	4.00 (11.3)	4.02 (7.8)	4.09 (15.3)	4.03 (5.7)	3.98 (12.6)	4.00 (5.0)	4.20 (12.1)	4.03 (5.6)	4.01 (15.9)	3.98 (4.4)	4.11 (18.5)
KC50S	1	mg/L	0.95 (14.45)	0.97 (35)	0.98 (15.6)	1.03 (40.8)	1.34 (14.0)	1.01 (38.7)	1.33 (17)	1.12 (17)	1.10 (20.0)	0.98 (59.0)	1.13 (16.9)	1.15 (59)
MDT	400	min			320.54 (18)	1279 (176.8)
Log10 mutf	-5				-5.77 (13.6)	-6.36 (16.3)	-5.24 (6.0)	-5.25 (17.2)	-5.22 (9.4)	-4.89 (19.5)			-5.20 (8.0)	-5.81 (25)
KC50R	4	mg/L					7.26 (40.0)	4.54 (36.0)	6.35 (41.6)	3.56 (73.0)			5.24 (27.7)	6.12 (346)
kfor	-6	Log10 (1/h)							-7.63 (7.9)	-7.11 (5.1)
krev	-1	Log10 (1/h)							< -10 (451)	-4.3 (309)
Smax	4										9.60 (29.0)	5.68 (107.0)	5.88 (44)	6.95 (191)
SC50	0.4	mg/L									0.86 (51.6)	0.25 (123.2)	0.51 (106)	0.28 (199)
MTTloss	20	h									46.62 (37.7)	35.43 (126.3)	40.47 (33)	81.83 (92)