Appendix A.

The placement of NR3C1 and FKBP5 methylation probes with their respective means and standard deviations in the FACHS, Hannum and AlcMeth cohorts.

				FACHS		Hannum		AlcMeth
CpG	Gene	Region	Island Status	Mean	Standard Deviation	Mean	Standard Deviation	Mean	Standard Deviation
cg12466613	NR3C1	TSS1500		0.895	0.029	0.925	0.038	0.746	0.036
cg07589972	NR3C1	TSS1500		0.869	0.027	0.916	0.031	0.804	0.027
cg26720913	NR3C1	1stExon		0.015	0.007	0.019	0.012	0.019	0.011
cg08818984	NR3C1	1stExon		0.057	0.017	0.052	0.021	0.070	0.020
cg07528216	NR3C1	5'UTR	S_Shelf	0.918	0.018	0.944	0.022	0.865	0.019
cg27345592	NR3C1	5'UTR	S_Shore	0.923	0.017	0.940	0.024	0.851	0.021
cg13648501	NR3C1	5'UTR	S_Shore	0.073	0.020	0.064	0.027	0.097	0.025
cg24026230	NR3C1	5'UTR	S_Shore	0.025	0.008	0.016	0.007	0.024	0.009
cg14558428	NR3C1	5'UTR	Island	0.024	0.008	0.016	0.008	0.018	0.008
cg21702128	NR3C1	TSS1500	Island	0.070	0.008	0.095	0.017	0.069	0.010
cg10847032	NR3C1	TSS1500	Island	0.042	0.008	0.053	0.010	0.048	0.012
cg16335926	NR3C1	TSS1500	Island	0.017	0.005	0.013	0.005	0.013	0.005
cg18849621	NR3C1	TSS1500	Island	0.055	0.013	0.054	0.015	0.059	0.018
cg06968181	NR3C1	TSS1500	Island	0.063	0.028	0.026	0.015	0.028	0.014
cg26464411	NR3C1	TSS1500	Island	0.067	0.028	0.027	0.011	0.034	0.010
cg18068240	NR3C1	5'UTR	Island	0.012	0.006	0.005	0.004	0.010	0.005
cg15645634	NR3C1	5'UTR	Island	0.028	0.008	0.017	0.006	0.025	0.007
cg15910486	NR3C1	5'UTR	Island	0.090	0.021	0.046	0.020	0.055	0.010
cgO4111177	NR3C1	5'UTR	Island	0.050	0.006	0.073	0.015	0.053	0.009
cg17860381	NR3C1	5'UTR	Island	0.035	0.011	0.014	0.008	0.014	0.005
cg18019515	NR3C1	TSS200	Island	0.011	0.004	0.006	0.004	0.008	0.004
cg11152298	NR3C1	TSS200	Island	0.062	0.006	0.080	0.011	0.064	0.009
cg00629244	NR3C1	TSS200	Island	0.014	0.007	0.007	0.005	0.016	0.007
cg18146873	NR3C1	1stExon	Island	0.034	0.010	0.047	0.019	0.044	0.010
cg20753294	NR3C1	1stExon	Island	0.062	0.020	0.039	0.028	0.055	0.018
cg17617527	NR3C1	5'UTR	Island	0.008	0.005	0.005	0.004	0.007	0.004
cg06521673	NR3C1	5'UTR	Island	0.040	0.007	0.043	0.008	0.044	0.008
cg06952416	NR3C1	5'UTR	N_Shore	0.068	0.027	0.041	0.027	0.074	0.032
cg27122725	NR3C1	5'UTR	N_Shore	0.109	0.029	0.088	0.040	0.060	0.028
cg18998365	NR3C1	5'UTR	N_Shore	0.551	0.039	0.580	0.053	0.533	0.040
cg07733851	NR3C1	5'UTR	N_Shore	0.320	0.039	0.354	0.057	0.344	0.037
cg08845721	NR3C1	5'UTR	N_Shore	0.827	0.041	0.891	0.033	0.794	0.031
cg17342132	NR3C1	Body	N_Shore	0.711	0.060	0.865	0.030	0.730	0.056
cg06613263	NR3C1	Body	N_Shelf	0.794	0.044	0.846	0.041	0.749	0.043
cg27107893	NR3C1	Body		0.860	0.035	0.897	0.053	0.743	0.053
cg25535999	NR3C1	Body		0.852	0.024	0.890	0.027	0.800	0.023
cg16586394	NR3C1	Body		0.866	0.026	0.901	0.023	0.837	0.021
cg18484679	NR3C1	Body		0.867	0.024	0.913	0.034	0.786	0.026
cg03857453	NR3C1	Body		0.754	0.051	0.700	0.051	0.757	0.049
cg19457823	NR3C1	Body		0.776	0.073	0.854	0.054	0.701	0.058
cg23273257	NR3C1	3'UTR		0.934	0.015	0.956	0.018	0.887	0.017
cg08915438	FKBP5	TSS1500	N_Shore	0.539	0.050	0.534	0.057	0.549	0.050
cg19226017	FKBP5	TSS1500	N_Shore	0.766	0.040	0.719	0.039	0.722	0.034
cg25114611	FKBP5	TSS1500	S_Shore	0.304	0.034	0.326	0.038	0.296	0.037
cg17030679	FKBP5	5'UTR	S_Shore	0.043	0.009	0.048	0.012	0.044	0.009
cg07485685	FKBP5	5'UTR	Island	0.030	0.009	0.016	0.010	0.017	0.006
cg00610228	FKBP5	5'UTR	Island	0.056	0.007	0.091	0.024	0.060	0.008
cg11845071	FKBP5	5'UTR	Island	0.010	0.006	0.006	0.005	0.011	0.006
cg06937024	FKBP5	5'UTR	N_Shore	0.032	0.015	0.012	0.006	0.008	0.004
cg00052684	FKBP5	5'UTR	N_Shore	0.393	0.062	0.470	0.056	0.338	0.071
cg23416081	FKBP5	5'UTR	N_Shelf	0.313	0.060	0.188	0.058	0.334	0.080
cg15929276	FKBP5	5'UTR		0.194	0.053	0.137	0.052	0.197	0.065
cg03591753	FKBP5	5'UTR	S_Shelf	0.547	0.068	0.472	0.048	0.587	0.065
cg08636224	FKBP5	5'UTR	S_Shore	0.896	0.036	0.908	0.017	0.876	0.016
cg00130530	FKBP5	5'UTR	S_Shore	0.612	0.052	0.631	0.040	0.607	0.048
cg20813374	FKBP5	5'UTR	S_Shore	0.411	0.049	0.404	0.040	0.399	0.046
cg01294490	FKBP5	TSS200	S_Shore	0.089	0.017	0.080	0.017	0.100	0.024
cg07843056	FKBP5	TSS200	Island	0.008	0.006	0.007	0.006	0.012	0.008
cg16012111	FKBP5	TSS200	Island	0.058	0.010	0.075	0.017	0.063	0.011
cg10913456	FKBP5	1stExon	Island	0.007	0.004	0.007	0.011	0.007	0.004
cg00140191	FKBP5	5'UTR	Island	0.045	0.014	0.025	0.013	0.028	0.010
cg00862770	FKBP5	5'UTR	Island	0.038	0.007	0.037	0.008	0.045	0.011
cg03546163	FKBP5	5'UTR	N_Shore	0.503	0.074	0.550	0.097	0.423	0.062
cg14642437	FKBP5	5'UTR	N_Shelf	0.844	0.027	0.842	0.035	0.797	0.026
cg17085721	FKBP5	5'UTR		0.856	0.025	0.907	0.020	0.844	0.025
cg19014730	FKBP5	5'UTR		0.651	0.050	0.726	0.055	0.579	0.050
cg07061368	FKBP5	5'UTR		0.813	0.045	0.880	0.042	0.729	0.045
cg08586216	FKBP5	5'UTR		0.916	0.012	0.938	0.014	0.903	0.014
cg16052510	FKBP5	Body		0.729	0.059	0.847	0.049	0.709	0.049
cg14284211	FKBP5	Body		0.246	0.050	0.151	0.047	0.225	0.054
cg07633853	FKBP5	Body		0.159	0.037	0.109	0.050	0.185	0.044
cg10300814	FKBP5	Body		0.881	0.019	0.890	0.020	0.860	0.016
cg06087101	FKBP5	Body		0.412	0.081	0.412	0.073	0.407	0.064
cg02665568	FKBP5	Body		0.865	0.027	0.891	0.032	0.800	0.025