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. Author manuscript; available in PMC: 2017 Apr 15.
Published in final edited form as: J Acquir Immune Defic Syndr. 2016 Apr 15;71(5):570–576. doi: 10.1097/QAI.0000000000000910

Table 4.

Comparison of first adequate anal cytology result with the biopsy result from subsequent high resolution anoscopy (HRA), among 94 men who had HRA within less than 12 months after anal cytology.

HRA Outcome/Biopsy
Cytology No intraepithelial lesions bLSIL bHSIL Total
Normal (negative) 8 4 1 13
ASC-US+ 43 16 22 81
Total 51 20 23 94
Utility of any abnormal ACyt for bHSIL % n/N
 Sensitivity 96% (22/23)
 Specificity 17% (12/71)
 Positive Predictive Value 27% (22/81)
 Negative Predictive Value 92% (12/13)

ASC-H/HSIL: Atypical squamous cells-cannot exclude high grade/High-grade intraepithelial lesion on anal cytology

bLSIL: Low-grade squamous intraepithelial lesion on biopsy

bHSIL: High-grade squamous intraepithelial lesion on biopsy