TABLE 2.
Adjusted/weighted and unadjusted/unweighted patient and tumor characteristics of the National Cancer Database study, by delay interval. Variables also included in the analysis, but not displayed below, are region, income, education, year of diagnosis, facility/cancer program type, mean distance to facility, and analytic case type. These are delineated in eTable 5 for space reasons.
| Characteristic | Adjusted % (Unadjusted %)* unless otherwise specified | ||||
|---|---|---|---|---|---|
| ≤30 days | 31–60 days | 61–90 days | 91–120 days | 121–180 days | |
| Total Patients | 80,505 | 28,832 | 4,697 | 1,152 | 604 |
| Mean age in years | 60.4 (60.1) | 60.5 (60.8) | 60.9 (60.8) | 60.6 (60.7) | 60.3 (61.3) |
| Gender | |||||
| Female | 99.1 (99.0) | 99.1 (99.3) | 98.7 (99.3) | ** | ** |
| Male | 0.9 (1.0) | 0.9 (0.7) | 1.3 (0.7) | ** | ** |
| Race | |||||
| White | 82.8 (85.4) | 82.9 (79.6) | 82.4 (71.0) | 80.7 (58.5) | 85.0 (57.0) |
| Black | 9.2 (7.6) | 9.1 (11.2) | 9.2 (16.7) | 9.6 (23.1) | 8.5 (26.0) |
| Asian | 2.1 (2.0) | 2.2 (2.3) | 2.3 (2.4) | 2.2 (3.0) | 1.7 (3.8) |
| Hispanic | 4.1 (3.2) | 4.0 (5.1) | 4.1 (8.2) | 5.0 (12.5) | 3.5 (10.8) |
| Other/Unknown | 1.8 (1.8) | 1.8 (1.8) | 1.9 (1.8) | 2.5 (2.9) | 1.4 (2.5) |
| Charlson Comorbidity Score† | |||||
| 0 | 88.1 (88.8) | 88.1 (87.4) | 87.9 (85.6) | 86.9 (84.2) | 88.0 (83.6) |
| 1 | 10.0 (9.6) | 10.1 (10.5) | 10.0 (11.4) | 10.9 (11.9) | 10.0 (12.4) |
| ≥2 | 1.8 (1.7) | 1.9 (2.1) | 2.1 (3.0) | 2.3 (3.9) | 2.0 (4.0) |
| Setting§ | |||||
| Large metropolitan | 51.3 (47.9) | 51.2 (57.9) | 51.3 (63.1) | 52.9 (67.5) | 46.9 (68.9) |
| Metropolitan | 32.6 (34.5) | 32.7 (29.1) | 32.5 (25.8) | 30.9 (23.0) | 35.2 (21.5) |
| Urban | 6.5 (7.0) | 6.5 (5.6) | 6.3 (4.9) | 6.3 (3.8) | 7.6 (4.3) |
| Less Urban/Rural | 9.6 (10.7) | 9.6 (7.5) | 9.9 (6.2) | 9.9 (5.6) | 10.3 (5.3) |
| Invasive Histology | |||||
| Ductal | 89.2 (89.5) | 89.3 (88.7) | 88.9 (88.6) | 87.4 (87.7) | 87.9 (87.3) |
| Lobular | 8.1 (7.7) | 8.1 (8.7) | 8.0 (8.6) | 9.5 (9.6) | 9.7 (8.9) |
| Other/unknown | 2.7 (2.8) | 2.7 (2.6) | 3.2 (2.8) | 3.1 (2.8) | 2.4 (3.8) |
| Grade | |||||
| Well differentiated | 21.0 (20.4) | 21.0 (22.5) | 20.9 (22.5) | 21.4 (18.4) | 19.7 (17.7) |
| Moderately differentiated | 39.7 (39.4) | 39.8 (40.3) | 40.1 (40.5) | 42.9 (43.0) | 40.9 (35.6) |
| Poorly differentiated | 32.6 (33.8) | 32.5 (30.2) | 31.9 (28.9) | 29.0 (29.9) | 32.8 (33.8) |
| Undifferentiated/Anaplastic | 0.9 (0.9) | 0.8 (0.8) | 0.9 (1.0) | 0.6 (1.7) | 0.5 (2.3) |
| Unknown | 5.8 (5.5) | 5.9 (6.2) | 6.3 (7.1) | 6.1 (7.0) | 6.1 (10.6) |
| Mean tumor size in cm | 2.1 (2.1) | 2.0 (2.0) | 2.1 (2.1) | 2.1 (2.1) | 2.2 (3.4) |
| AJCC Stage‡ | |||||
| I | 52.1 (51.6) | 52.2 (53.6) | 51.9 (52.1) | 50.2 (50.4) | 48.0 (41.6) |
| II | 37.2 (37.6) | 37.0 (36.3) | 37.2 (35.6) | 39.3 (34.9) | 40.4 (38.9) |
| III | 10.8 (10.7) | 10.8 (10.1) | 11.0 (12.4) | 10.5 (14.7) | 11.7 (19.5) |
| Surgical Margins: Residual Tumor | |||||
| None | 94.6 (94.8) | 94.6 (94.4) | 94.3 (93.6) | 94.6 (91.1) | 95.6 (92.4) |
| Residual | 4.3 (4.2) | 4.3 (4.3) | 4.7 (4.6) | 4.2 (6.4) | 3.3 (4.8) |
| Other/Unknown | 1.1 (1) | 1.1 (1.3) | 1.1 (1.8) | 1.2 (2.5) | 1 (2.8) |
| Mean # Nodes Examined | 7.8 (7.8) | 7.8 (7.7) | 7.8 (8.2) | 7.8 (8.7) | 8.5 (9.4) |
| Mean # Nodes Positive | 1.2 (1.2) | 1.2 (1.1) | 1.2 (1.3) | 1.2 (1.4) | 1.4 (1.9) |
| Surgery Type | |||||
| Breast Conservation | 62.9 (65.4) | 63 (58.9) | 63.7 (51.9) | 60.3 (48.2) | 64.4 (45.5) |
| Mastectomy | 37.1 (34.6) | 37 (41.1) | 36.3 (48.1) | 39.7 (51.8) | 35.6 (54.5) |
| Chemotherapy Use | |||||
| Yes | 37.1 (34.6) | 37 (41.1) | 36.3 (48.1) | 39.7 (51.8) | 35.6 (54.5) |
| No | 62.9 (65.4) | 63 (58.9) | 63.7 (51.9) | 60.3 (48.2) | 64.4 (45.5) |
| Radiotherapy Use | |||||
| Yes | 62.8 (65.5) | 62.7 (58.7) | 63.3 (50.6) | 60.4 (44.8) | 65.4 (40.9) |
| No | 37.2 (34.5) | 37.3 (41.3) | 36.7 (49.4) | 39.6 (55.2) | 34.6 (59.1) |
| Endocrine Therapy Use | |||||
| Yes | 52.5 (53.1) | 52.5 (52.8) | 51.5 (48) | 51.7 (43.1) | 53.5 (36.6) |
| No | 47.5 (46.9) | 47.5 (47.2) | 48.5 (52) | 48.3 (56.9) | 46.5 (63.4) |
| Insurance Type | |||||
| None | 2.0 (1.8) | 2.0 (2.2) | 2.0 (3.3) | 1.9 (5.1) | 1.9 (5.5) |
| Private | 16.5 (17.8) | 16.5 (13.9) | 16.6 (12.1) | 17.2 (10) | 17.6 (9.6) |
| Managed Care | 39.2 (39.2) | 39 (40.6) | 37.1 (36.5) | 38.3 (33.9) | 36.4 (30.1) |
| Medicaid | 4.3 (3.5) | 4.3 (5.2) | 4.6 (8.2) | 4.8 (11.1) | 4.5 (10.9) |
| Medicare | 35 (34.6) | 35.3 (35.4) | 37.2 (35.7) | 35.5 (33.5) | 38.1 (36.9) |
| Other Government/Unknown | 3.0 (3) | 2.9 (2.7) | 2.4 (4.2) | 2.4 (6.3) | 1.6 (7.0) |
Totals may vary from 100% due to rounding.
Cells have been deleted as per NCDB requirements to censor cells containing <11 individuals, or other cells that make such cells calculable.
Charlson scores of ≥2 are collapsed together into one group and so mean Charlson scores for NCDB data cannot be calculated.
Setting definitions: Large metropolitan = counties of metropolitan areas of ≥1,000,000; metropolitan = counties in metropolitan areas of <250,000–1,000,000; urban = urban population of ≥20,000 adjacent or nonadjacent to a metropolitan area; less urban = urban population of 2,500–19,999 adjacent or nonadjacent to a metropolitan area; rural = completely rural or <2,500 urban population, adjacent or nonadjacent to a metropolitan area.
AJCC Stage: 5rd and 6th editions were combined. Substages (e.g. IIA, IIB) were collapsed to minimize differences between these AJCC Editions.