Figure 5.
Effect of rivastigmine treatment on protein expression of synaptic markers. Representative Western blots and densitometry analysis of pre-synaptic marker (SNAP-25), postsynaptic marker (PSD-95) and glutamate transporter 1 (GLT1) from brain homogenates of APP/mdr1+/+ (A), APP/mdr1+/− (B) and APP/mdr1−/− (C) mice following treatment with rivastigmine or vehicle. Data presented as mean±SEM (n = 3–6, * P<0.05, ** P<0.01, *** P<0.001 compared to vehicle-treated controls).