Table 1.
Concentration of lutein (L), zeaxanthin (Z) and meso-zeaxanthin (MZ) in eye care supplements
| Supplement name, manufacturer, carotenoid supplier | Batch number | Months expiry | Carotenoids (mg/capsule) | % Achieved (95 % confidence) | ||
|---|---|---|---|---|---|---|
| Declared | Measured | |||||
| Preservision AREDS2 ®b | 2710E0566 | 16 | L | 5 | 6.05 ± 0.27 | 121 (117–125) |
| Bausch + Lomb®└ | 2936E0566 | 16 | Z | 1 | 1.63 ± 0.11 | 163 (155–172) |
| Floraglo® Lutein | 2939E0566A | 16 | MZ | * | nd | – |
| VitaluxPlus ®a | E02010 | 13 | L | 10 | 11.12 ± 0.52 | 111 (107–115) |
| Alcon® | E05507 | 16 | Z | 2 | 1.03 ± 0.07 | 52 (49–54) |
| Floraglo® Lutein | E03745 | 15 | MZ | * | 0.10 ± 0.01 | – |
| Nutrof ® omega a | V067 | 10 | L | 10 | 9.54 ± 0.67 | 95 (90–101) |
| Spectrum Thea® | V070 | 12 | Z | 2 | 1.30 ± 0.27 | 47 (44–50) |
| Floraglo® Lutein | V063 | 8 | MZ | * | 0.94 ± 0.08 | – |
| Ultra Lutein ®a,c | 1266679 | 17 | L | 20 | 20.78 ± 0.73 | 104 (101–107) |
| Nature’s Plus® | 1263243 | 14 | Z | 0.86 | 2.13 ± 0.09 | 248 (240–256) |
| Floraglo® | 1268878 | 17 | MZ | * | 0.18 ± 0.03 | – |
| Eyepromise Restore ®b | C1401047 | 28 | L | 4 | 4.83 ± 0.14 | 121 (118–123) |
| Zeavision® | H13059 | 22 | Z | 8 | 1.28 ± 0.07# | 16 (15–17) |
| Floraglo® Lutein, Zeagold® | B14045 | 28 | MZ | * | 0.04 ± 0.01 | – |
| CentroVision ® L forte a | 5054 | 15 | L | 14 | 13.91 ± 0.45 | 99 (97–102) |
| OmniVision GmbH® | 4581 | 10 | Z | 1.04 | 1.68 ± 0.08 | 161 (156–167) |
| Floraglo® Lutein | 8180 | 10 | MZ | * | 0.11 ± 0.01 | – |
| MacuHealth with LMZ3 ® d | 110614 | 29 | L | 10 | 10.89 ± 1.34 | 109 (99–119) |
| Macuhealth LLC® | 160314 | 26 | Z | 2 | 2.19 ± 0.49 | 109 (90–128) |
| IOSA® | 330913 | 20 | MZ | 10 | 12.15 ± 2.14 | 122 (105–138) |
| MacuShield ® d | 116215 | 11 | L | 10 | 12.11 ± 0.91 | 121 (114–128) |
| Macuvision Europe® | 118860 | 21 | Z | 2 | 2.51 ± 0.25 | 126 (116–135) |
| IOSA® | 120480 | 26 | MZ | 10 | 12.70 ± 0.74 | 127 (121–133) |
| Ocuvite ® L Plus a | D09592 | 10 | L | 5 | 5.53 ± 0.26 | 111 (107–115) |
| Bausch + Lomb® | D09588 | 10 | Z | 1 | 0.60 ± 0.03 | 60 (57–62) |
| Unknown | D09591 | 10 | MZ | * | 0.79 ± 0.03 | – |
Carotenoid amounts are provided in mg/capsule ± standard deviation, and as percentage of declared concentration achieved, including 95 % confidence interval
aSourced in pharmacy
bSourced online
cSourced in health food store
dSourced by the manufacturer
* Carotenoid not declared in product label, nd, carotenoid not detected
– Non-applicable
# Quantification not including esterified Z