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. 2016 Mar 8;110(5):1089–1098. doi: 10.1016/j.bpj.2016.01.006

Figure 2.

Figure 2

PIP2 regulates the voltage-activation properties of neuronal KCNQ channels in the presence of BACE1. (a) Left: representative current traces at different membrane potentials from HEK293T cells coexpressing KCNQ2/3, PIPKIγ90, and BACE1 (n = 10). Right: normalized G-V relationship to the maximum tail current at −70 mV. (b) Left: representative current traces at different membrane potentials from cells coexpressing KCNQ5, PIPKIγ90, and BACE1 (n = 3). Right: normalized G-V relationship to the maximum tail current at −70 mV. Data represent mean ± SEM. To see this figure in color, go online.