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Pharmacokinetic parameters of AZT in plasma after a single-dose administration of 600 mg AZT.
| Parameter | AZT |
|---|---|
| Cmax (μg/L) | 3505.176±362.932 |
| Tmax (h) | 0.583±0.195 |
| AUC0-t (μg·h/L) | 7050.142±1275.517 |
| AUC0-∞ (μg·h/L) | 7167.961±1267.624 |
| t1/2 (h) | 2.022±0.946 |
| MRT0-t (h) | 2.197±0.253 |
| MRT0-∞ (h) | 2.404±0.216 |
| Vd/F (L) | 263.908±161.840 |
| CL/F (L/h) | 86.092±14.962 |
Each value represents the mean±SD, unless otherwise specified, n=12.
