Table 1.
Baseline characteristics of study participants—characteristics shown as median (range). HV: healthy volunteers; T2DM: patients with type 2 diabetes mellitus.
| HV: assessment of GLP-1 concentrations n = 10 |
HV: assessment of glucose tolerance n = 9 |
HV: assessment of meal sizea n = 10 |
T2DM: assessment of glucose tolerance n = 8 |
|
|---|---|---|---|---|
| Gender | 5 male, 5 female | 4 male, 5 female | 5 male, 5 female | 4 male, 4 female |
| Age (years at enrolment) | 31.3 (9.7) | 36.2 (10.5) | 33.9 (10.2) | 57.9 (10.7) |
| Body Mass Index (kg/m2) | 22.9 (3.5) | 25.0 (3.9) | 23.4 (4.1) | 32.5 (5.6) |
| Waist circumference (cm) | 79.0 (14.0) | 88.3 (11.5) | 83.1 (15.5) | 104.0 (16.8) |
| Hip circumference (cm) | 94 (10) | 102 (8) | 96 (11) | 120 (10) |
| DXA percentage fat mass | 23.8 (11.3) | 29.3 (12.5) | 29.1 (12.4) | 41.8 (8.0) |
| Hemoglobin (g/l) | 136 (13) | 138 (14) | 135 (15) | 136 (16) |
| White Cell Count *109/l | 5.1 (0.7) | 5.3 (1.1) | 4.8 (1.0) | 6.7 (1.0) |
| Platelets *109/l | 189 (25) | 225 (52) | 197 (30) | 165 (82) |
| Creatinine (μmol/l) | 70.5 (11.8) | 67.3 (11.0) | 64.0 (8.9) | 70.9 (10.4) |
| ALT (IU/l) | 32.5 (23.8) | 36.4 (25.9) | 33.6 (27.6) | 46.0 (23.3) |
| TSH (U/l) | 2.0 (0.8) | 2.1 (0.6) | 2.0 (0.9) | 1.9 (1.0) |
| HbA1c (mmol/mol) | 36.0 (4.2) | 36.9 (3.4) | 36.4 (3.6) | 57.6 (17.6) |
a
Only 8 of these participants had blood taken and a DXA scan.