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. Author manuscript; available in PMC: 2017 Mar 10.
Published in final edited form as: Cell. 2016 Mar 10;164(6):1162–1171. doi: 10.1016/j.cell.2016.01.034

Figure 2. Overall structure of the NPC.

Figure 2

Cryo-electron tomographic (cryo-ET) reconstruction of the human NPC from HeLa cells (EMDB code 3103, (Appen et al., 2015)). Cut-away view showing half of an NPC embedded in the nuclear envelope (yellow). Additional structural elements, i.e., cytoplasmic filaments and nuclear basket that have been excluded from the cryo-ET analysis, are added schematically. Nucleoporins from yeast and metazoa are listed and color-matched according to their approximate positions within the NPC.