Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Mar 11;13:8. doi: 10.1186/s12950-016-0117-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Fallows et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 1 — M. leprae and its lipid component PGL-1 alter the release of cytokines and chemokines from M1 polarized monocytes. CD14⁺ cells were polarized towards M1 phenotype (M1) or pre-exposed for 5 h to the following: a-b M. leprae (MOI 5:1, Lep5 or 20:1, Lep20), c PGL-1 (50 μg/mL) or cultured in medium alone (UN). Cell supernatants were collected at 48 h and cytokines/chemokines analyzed. Results are the mean ± Sem: a-b 8 experiments (8 independent donors); and c 6 experiments (6 independent donors) performed in duplicate. A 2-tailed paired t-test was used for statistical analysis (*P ≤ 0.05, relative to M1 cells)