Table 1.
Phenotypic markers | |||
---|---|---|---|
CCR7 | CD40 | CD80 | |
M1 cells | 248.0 ± 31.7 | 51.6 ± 6.3 | 765.0 ± 64.2 |
Lep5 (5 h)/M1 | 167.1** ± 22.6 | 40.4* ± 6.5 | 681.9 ± 77.6 |
Lep20 (5 h)/M1 | 152.2* ± 7.9 | 46.3 ± 7.8 | 591.0* ± 70.1 |
Unstimulated cells | 44.3** ± 1.7 | 6.5*** ± 0.3 | 16.6*** ± 2.8 |
Lep5 | 48.4** ± 1.6 | 7.8*** ± 0.3 | 20.3*** ± 2.8 |
Lep20 | 49.3** ± 1.4 | 7.8** ± 0.4 | 25.3*** ± 3.3 |
The values represent the mean MFI ± Sem of 4–7 independent experiments (independent donors) for each condition. The statistical significance is shown as compared to the M1 cells. Lep5 (M. leprae MOI 5:1); Lep20 (M. leprae MOI 20:1).*P ≤ 0.05; **P ≤ 0.001 and ***P ≤ 0.0001