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. 2016 Mar 11;17:221. doi: 10.1186/s12864-016-2477-9

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© Gardiner et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Immunolabeling in normal and mutant retinas for retinal transcription factors. A CRX; B NRL; C PAX6. Samples were from normal (7 wks), xlpra2 (8 wks), rcd1 (7 wks) and erd (CRX-9.1 wks; NRL-7.7 wks; PAX6-14.1 wks). In normal, xlpra2 and rcd1, NRL is expressed in cone outer segments (B1 arrowheads and corresponding locations in B2 and B3) and in the basal aspect of the outer nuclear layer; the rcd1 retina has few rods, and almost no rod outer segments remain so NRL distinctly labels the surviving cone outer segments. PR = photoreceptor, ONL = outer nuclear layer, INL = inner nuclear layer, IPL = inner plexiform layer, NFL = nerve fiber layer. Scale bar = 40 μm