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. 2016 Mar 11;9:144. doi: 10.1186/s13071-016-1413-9

Table 2.

Inoculation route and parasite dose influences on visceral leishmaniasis outcome in susceptible BALB/c mice

Infection route Parasite dose Parasite strain Liver load Spleen load Th1 response Th2 response Reference
Subcutaneous 105 LIVT-1 + - ND ND [32]
106 + + ND ND
107 + + ND ND
103 MHOM/BR/1970/BH46 +/- ++ + + [33]
105 + +++ + +
107 ++ ++++ + +++
103 MHOM/IN/80/DD8 +/- ND +++ + [34]
105 + ND ++ +
107 + ND ++ ++
Intradermal 103 MHOM/IN/80/DD8 + ND +++ + [34]
105 ++ ND ++ +
107 ++ ND ++ +
107 MHOM/ES/92/LLM-320 +++ +++ + + [38]
Intraperitoneal 103 MHOM/IN/80/DD8 ++ ND ++ ++ [34]
105 +++ ND + ++
107 +++ ND + +++
107 MCAN/PT/94/IMT205 ND + ND ND [37]
Intracardiac 103 MHOM/IN/80/DD8 ++ ND ++ ++ [34]
105 +++ ND + ++
107 ++++ ND - +++
107 MHOM/IN/1993/B12302 +++ ++ ++ ++ [35]
Intravenous 105 LIVT-1 + + ND ND [32]
106 ++ + ND ND
107 +++ + ND ND
107 MHOM/BR/1970/BH46 + + + ++ [33]
103 MCAN/ES/96/BCN150 + + +/- - [36]
105 ++ ++ +/- +/-
106 ++ +++ + ++
104 MHOM/ES/92/LLM-320 +/- + ND ND [38]
105 + ++ ND ND
106 ++ +++ ND ND
107 MCAN/PT/94/IMT205 ND + ND ND [37]

ND not done