Table 1.
The KEGG pathway enrichment analysis for the genes with number of transcripts greater than 3
| Genes with Ntr > 3 | ||
|---|---|---|
| KEGG pathway | Number of genes | p EASE score |
| Calcium signaling pathway (b,c) | 40 | 8.43 10−4 |
| Pathways in cancer (a) | 64 | 1.54 10−3 |
| p53 signaling pathway (a) | 19 | 2.93 10−3 |
| MAPK signaling pathway (a) | 51 | 7.68 10−3 |
| Apoptosis (a) | 21 | 9.85 10−3 |
| Acute myeloid leukemia (a) | 15 | 1.88 10−2 |
| ErbB signaling pathway | 20 | 2.00 10−2 |
| NOD-like receptor signaling pathway | 15 | 3.25 10−2 |
| Thyroid cancer (a) | 9 | 3.29 10−2 |
| Progesterone-mediated oocyte maturation | 19 | 3.44 10−2 |
| Hematopoietic cell lineage | 19 | 3.44 10−2 |
| Neurotrophin signaling pathway | 25 | 3.87 10−2 |
| Wnt signaling pathway | 29 | 4.45 10−2 |
| Prostate cancer (a) | 19 | 4.65 10−2 |
| Adherens junction | 17 | 4.71 10−2 |
The significantly enriched KEGG pathways are revealed via DAVID gene functional annotation server, taking Homo sapiens as a correction background. The p EASE significance scores for the enrichment are shown along with the number of hit genes. The notations in the brackets mark the pathways linked to cancer (a), neurological (b) and cardiological (c) conditions. The full list of genes that appear in each enriched pathway can be found in Additional file 3