Figure 1.

(a) Simulated C_p and C_e curves for an 8% vascular volume fraction and 60% cell volume fraction using a two-compartment model and PFM. (b-c) Simulated ΔR₂* curves for no leakage, uncorrected, and corrected using $r_{2,t}^{\ast }{\mathrm{C}}_{\mathrm{t}}$ (b, Method 2) and $r_{2,e}^{\ast }{\mathrm{v}}_{\mathrm{e}}{\mathrm{C}}_{\mathrm{e}}$ (c, Method 3). (d) Bar plots showing the CBV percent difference between the true CBV and the uncorrected and corrected CBV.