Table 2.
Descriptive statistics with regression analysis
| Factors | Non-IgM MGUS (N = 223) |
IgM MGUS (N = 58) |
Univariate regression analysis | Multivariate regression analysis | |||
|---|---|---|---|---|---|---|---|
| Odds ratio P value (95 % CI) |
Odds ratio P value (95 % CI) |
||||||
| Race | Caucasians All others |
116 (52 %) 107 (48 %) |
48 (83) 10 (17) |
4.43 (2.13, 9.19) |
<0.001 | 3.77 (1.70, 8.38) | <0.001 |
| Gender | Male Female |
103 (46 %) 120 (54 %) |
30 (52 %) 28 (48 %) |
1.25 (0.70, 2.23) |
0.452 | ||
| MGUS Age (in years) | Mean ± SD | 67.9 ± 12.6 | 68.1 ± 14.9 | 1.21 (0.62, 2.36) | 0.495 | ||
| M-spike (quantitative) on presentation (mg/dL) | Mean ± SD | 1541.2 ± 1496.4 | 559.6 ± 569.6 | 0.998 (0.997, 0.998) | <0.001 | 0.977 (0.97, 0.985) | <0.001 |
| Neuropathy age (in years) | Mean ± SD | 68.0 ± 13.0 | 68.2 ± 14.1 | 1.01 (0.53, 1.93) | 0.659 | ||
| Survival status | Alive Deceased |
187 (84 %) 36 (16 %) |
42 (72 %) 16 (28 %) |
1.98 (1.01, 3.90) |
0.046 | ||
| Neuropathy type | Sensory Non-sensory |
58 (26 %) 165 (74 %) |
16 (28 %) 42 (72 %) |
1.08 (0.57, 2.07) |
0.808 | ||
| Location of Neuropathy | Extremities Other |
213 (96 %) 10 (4 %) |
54 (93 %) 4 (7 %) |
1.58 (0.48, 5.23) |
0.455 | ||
| Duration of neuropathy | Less than 1 year 1 year or more |
30 (13 %) 193 (87 %) |
8 (14 %) 50 (86 %) |
0.97 (0.42, 2.25) |
0.946 | ||
| Therapy used | Conservative Non-conservative |
97 (43 %) 126 (57 %) |
30 (52 %) 28 (48 %) |
0.72 (0.40, 1.28) |
0.263 | ||
| Response to therapy | Yes No |
175 (78 %) 48 (22 %) |
44 (76 %) 14 (24 %) |
0.86 (0.44, 1.70) |
0.669 | ||
| Evolution of MGUS | Yes No |
32 (14 %) 191 (86 %) |
6 (10 %) 52 (90 %) |
0.69 (0.27, 1.74) |
0.429 | ||