Skip to main content
. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Neurotoxicol Teratol. 2016 Jan 28;54:15–21. doi: 10.1016/j.ntt.2016.01.004

Figure 1. Pre-ischemic treatment with tBHQ increases mortality and does not improve neurological score in the murine pMCAO model.

Figure 1

(A). Schematic diagram summarizing the injection and stroke timeline. The short arrows represent time points of tBHQ injection. (B). Mortality after 24 hr pMCAO. Vehicle, n=11, tBHQ 0.582 mg/kg, n=8, tBHQ 3.34 mg/kg, n=8, tBHQ 33.4 mg/kg, n=10. (C). Neurological score after pMCAO. Data are expressed as mean ± SD. Vehicle, n=11, tBHQ 0.582 mg/kg, n=8, tBHQ 3.34 mg/kg, n=8, tBHQ 33.4 mg/kg, n=8. One-way ANOVA followed by post hoc Tukey test and Chi-Square test were used for multiple group comparison. #P < 0.05, ##P < 0.01 compared to vehicle.