Ipsilateral (A) and contralateral (B) brain volumes were measured at 24 hr after ischemia induction. Representative coronal sections were used to analyze brain volume of mice treated with vehicle vs tBHQ. Vehicle, n=11, tBHQ 0.582 mg/kg, n=8, tBHQ 3.34 mg/kg, n=8, tBHQ 33.4 mg/kg, n=8. Mean ± SD; One-way ANOVA followed by post hoc Tukey test was used for multiple group comparison. #P < 0.05, ##P < 0.01 compared to vehicle.