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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Neurotoxicol Teratol. 2016 Jan 28;54:15–21. doi: 10.1016/j.ntt.2016.01.004

Figure 5. tBHQ exacerbates LPS-induced mitochondrial inhibition in the bEnd.3 cell line.

Figure 5

(A) Bioenergetics functional assay exposed to LPS and various concentration of tBHQ compared with vehicle control for 24 hr. Basal respiration (B), ATP production (C), maximal respiration (D), and spare capacity (E) were calculated from the assay and presented. Mean ± SD; n=4 per group; One-way ANOVA followed by post hoc Tukey test was used for data analysis. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.00001 compared to control. #P < 0.05, ##P < 0.01, ###P < 0.001, ####P < 0.00001 compared to LPS treatment.