Table 4.
ΔM/M | Tau (sec) | T1 (sec) | kf (sec−1) | Normalized CK flux rate | |
---|---|---|---|---|---|
Baseline | 0.64±0.07 | 1.37±0.12 | 4.33±0.84 | 0.47±0.06 | 1 |
8-PT | 0.62±0.07 | 1.17±0.14 | 3.28±0.37 | 0.58±0.14 | 1.13±0.26 |
8-PT+GLIB | 0.66±0.06 | 1.47±0.07 | 4.55±0.82 | 0.48±0.04 | 0.73±0.08* |
Values are means ± SE. 8-PT, 8-Phenyltheophylline at 5mg/kg intravenous; GLIB, Glibenclamide at 20 μg/kg/min intracoronary; ΔM/M, relative change of PCr resonance intensity; Tau, time constant that fits the integral of PCr magnetization decay as the time of saturation of ATPγ increased from 0 to infinite; T1, longitudinal relaxation time; kf, forward rate constant of creatine kinase;
p<0.05 vs. baseline.