Table 1.
Morphometric analyses of regenerated nerves for experimental groups (mean±D(
| Groups |
|||||||||
|---|---|---|---|---|---|---|---|---|---|
| Days | Sham | Treatment (crush + CoQ10) |
Un-treated (crush + soybean oil) |
||||||
| Parameters | 90 | 7 | 14 | 57 | 90 | 7 | 14 | 57 | 90 |
| No. of fibers | 8024 ±385 |
3356 ±167* |
3754 ±238* |
3854 ±178* |
6797 ±211* |
2935 ±157 |
3289 ±137 |
3187 ±148 |
6211 ±226 |
| Diameter of fibers (µm) | 12.01 ±0.01 |
2.59 ±0.33* |
4.48 ±0.53* |
8.49 ±0.42* |
9.75 ±0.92* |
2.16 ±017 |
3.36 ±0.47 |
6.56 ±0.49 |
7.72 ±0.89 |
| Diameter of axon (µm) | 7.06 ±0.02 |
2.24 ±0.28* |
3.63 ±0.43* |
4.87 ±0.59* |
5.36 ±0.24* |
2.15 ±0.19 |
2.52 ±0.37 |
3.53 ±0.62 |
3.68 ±0.63 |
| Myelin thickness (µm) | 2.53 ±0.01 |
0.15 ±0.01* |
0.53 ±0.02 |
2.37 ±0.25* |
2.33 ±0.46 |
0 | 0.47 ±0.02 |
1.59 ±0.11 |
2.42 ±0.52 |
| G-ratio | 0.59 | 0.87 | 0.81 | 0.57 | 0.56 | 0.99 | 0.75 | 0.54 | 0.49 |
*
P<0.05 vs. un-treated group. G-ratio: Ratio of axon diameter to fiber diameter