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. 2015 Nov 24;4(1):1–6. doi: 10.1016/j.prnil.2015.08.001

Table 2.

The Risk of Prostate Cancer Relating to Obesity in Various Studies Based on Obesity Status (Body Mass Index and Waist Circumference).

Study reference Population studied (n) Control (n) Findings
De Nunzio et al22
  • •

    PCa (246)
  • •

    Control (422)

 Central adiposity was significantly associated with PCa (OR 1.66, CI 95% 1.05–2.63, P = 0.03) and high-grade disease (OR 2.56, CI 95% 1.38–4.76, P = 0.003)
Nemesure et al70
  • •

    PCa (963)
  • •

    Control (941)

 WC of ≥ 102 cm had an OR of 1.84 (95% CI 1.19–2.85) compared with those with WC of < 90 cm
Irani et al69
  • •

    PCa (194)
  • •

    Control (194)

 Obesity was significantly associated with PCa (OR 2.47, 95% CI 1.41–4.34)
De Nunzio et al68
  • •

    PCa (363)
  • •

    Control (522)

 Obesity was significantly associated with PCa (OR 1.097, 95% CI 1.029–1.171)
Rundle et al72
  • •

    PCa (494)
  • •

    Control (494)

 Obesity at the time of biopsy was associated with PCa incidence during follow-up (OR 1.57; 95% CI 1.07–2.30)
Park et al71
  • •

    Obese (408)
  • •

    Normal weight (805)

 Obesity was significantly associated with a higher risk of detection on PCa in biopsy patients (OR = 1.446, P = 0.024)
Obesity was significantly associated with a higher rate of high-grade PCa detected from the biopsy (OR = 1.498, P = 0.039)

BMI, body mass index; CI, confidence interval; OR, odds ratio; PCa, prostate cancer; WC, waist circumference.