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Heterogeneity of variability across subjects for phe measurement. Each line represents the range of percent differences from maximum to minimum within 3–4 sample pairs for each subject. Percent difference is defined as (plasma phe-blood phe)/plasma phe). x 100 The circle in the middle of each line represents the mean percent difference by subject. Total variability is high (SD = 13.2%) for 110 samples pairs from 29 subjects.
