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Extraction recovery of phe and tyr from dried blood spots (DBS) using tandem mass spectrometry (MS/MS) and ion-exchange chromatography (IEC).
| Percent extraction recovery (mean ± SD) |
||||
|---|---|---|---|---|
| Phe |
Tyr |
|||
| DBS-MS/MS | DBS-IEC | DBS-MS/MS | DBS-IEC | |
| 1500 μM spiked (n = 3) | 78 ± 3% | 104 ± 2% | 76 ± 4% | 108 ± 2% |
| 500 μM spiked (n = 3) | 62 ± 3% | 90 ± 1% | 60 ± 3% | 88 ± 1% |
| 100 μM spiked (n = 3) | 66 ± 3% | 86 ± 7% | 70 ± 2% | 93 ± 1% |
